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The ultimate goal of this study is to identify effective means for increasing healthy life expectancy.
The participants underwent extensive h phenotyping, including an hour-long recording of beat-by-beat blood pressure, magnetic resonance imaging of the brain and abdomen, and serum lipidomic profiling with LC-ESI-MS.
These assessments are complemented by a detailed evaluation of each participant in a of domains, including cognition, mental health Top Montreal sex websites substance use, diet, physical activity and sleep, and family environment. The data collection took place during —12 in adolescents full and their parents partialand during World sex guide Saguenay in parents.
All data are available upon request. It is aimed at investigating the aetiology, early stages and trans-generational trajectories of common cardiometabolic and brain diseases. The ultimate goal is to identify effective means for increasing healthy life expectancy. The de World sex guide Saguenay the SYS was motivated by the following biomedical considerations: i many common cardiometabolic and brain diseases originate in utero ; ii they involve interactions between adverse environments and vulnerability genes; iii many of these diseases emerge during adolescence and become established during middle-aged adulthood; and iv most of them are multi-systemic, affecting Find Shawinigan girlfriend Shawinigan the brain World sex guide Saguenay the rest of the body.
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Finally, the SYS was deed as a retrospective study of long-term outcomes of Massage North Vancouver hills North Vancouver exposure to maternal cigarette smoking.
The choice of this particular prenatal adversity reflected high prevalence of maternal cigarette smoking during pregnancy 23 and the reports of long-term cardiometabolic 4—6 and behavioural 7—10 abnormalities in the exposed offspring. The SYS cohort includes adolescents and their parents.
The cohort was recruited via adolescents attending high schools World sex guide Saguenay the Saguenay—Lac-Saint-Jean region of Quebec, Sluts with phones in Canada.
The region is home to the largest genetic founder population in North America. Half of the adolescents were exposed prenatally to maternal World sex guide Saguenay smoking. The cohort is family based familiesincluding only adolescents who have one or more siblings of similar age 12 to 18 years and both biological parents of the French-Canadian origin born in the region.
The data collection World sex guide Saguenay in two waves. Table 1. Basic characteristics of participants. Wave 1 took place over a year period — Recruitment was conducted via high schools. Based Ethiopian women in Shawinigan the inclusion e. From these, families participated in the study.
Maternal cigarette smoking before and during pregnancy was ascertained retrospectively by a research nurse who conducted a structured telephone interview with the mother. Wave 2 took place during a 3-year period between and World sex guide Saguenay contacted all parents by mail and telephone.